| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein P |
|---|
| Ligand | BDBM427507 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | HBV Replication Inhibition Assay |
|---|
| EC50 | 55±n/a nM |
|---|
| Citation |  Hartman, GD; Kuduk, S Derivatives and methods of treating hepatitis B infections US Patent US10544141 Publication Date 1/28/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein P |
|---|
| Name: | Protein P |
|---|
| Synonyms: | P | Q9WRL0_HBV | polymerase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 94822.25 |
|---|
| Organism: | HBV |
|---|
| Description: | Q9WRL0 |
|---|
| Residue: | 845 |
|---|
| Sequence: | MPLSYQHFRKLLLLDDGTEAGPLEEELPRLADADLNRRVAEDLNLGNPNVSIPWTHKVGN
FTGLYSSTVPIFNPEWQTPSFPKIHLQEDIINRCEQFVGPLTVNEKRRLKLIMPARFYPT
HTKYLPLDKGIKPYYPDQVVNHYFQTRHYLHTLWKAGILYKRETTRSASFCGSPYSWEQE
LQHGRLVIKTSQRHGDESFCSQPSGILSRSSVGPCIRSQLKQSRLGLQPHQGPLASSQPG
RSGSIRARVHPSTRRCFGVEPSGSGHVDPSVNNSSSCLRQSAVRKAAHSHLSTSKRQSSS
GDAVEFHCLPPSSARPQSQGSVFSCWWLQFRNSKPCSEYCLSHIVNLREDWGPCDEHGEH
HIRIPRTPARVTGGVFLVDKNPHNTEESRLVVDFSQFSRGITRVSWPKFAVPNLQSLTNL
LSSNLSWLSLDVSAAFYHIPLHPAAMPHLLIGSSGLSRYVARLSSNSRINNNQYGTMQNL
HDSCSRQLYVSLMLLYKTYGWKLHLYSHPIVLGFRKIPMGVGLSPFLLAQFTSAICSVVR
RAFPHCLAFSYMDDVVLGAKTVQHRESLYTAVTNFLLSLGIHLNPNKTKRWGYSLNFMGY
VIGSWGTLPQDHIVQKIKHCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLY
ACIQAKQAFTFSPTYKAFLSKQYMNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGT
FVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFV
YVPSALNPADDPSRGRLGLSRPLLRLPFQPTTGRTSLYAVSPSVPSHLPVRVHFASPLHV
AWRPP
|
|
|
|---|
| BDBM427507 |
|---|
| n/a |
|---|
| Name | BDBM427507 |
|---|
| Synonyms: | US10544141, Compound 966 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H21BrN4O2 |
|---|
| Mol. Mass. | 405.289 |
|---|
| SMILES | CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1cccc(Br)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
