| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(3) dopamine receptor |
|---|
| Ligand | BDBM50154900 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | [3H]-Spiperone Binding Assay |
|---|
| Ki | 2.95±n/a nM |
|---|
| Citation |  Cremonesi, S; Micheli, F; Semeraro, T; Tarsi, L Substituted 3,6-diazabicyclo[3.2.0]heptanes US Patent US10584135 Publication Date 3/10/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(3) dopamine receptor |
|---|
| Name: | D(3) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 44243.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 400 |
|---|
| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
|
|
|
|---|
| BDBM50154900 |
|---|
| n/a |
|---|
| Name | BDBM50154900 |
|---|
| Synonyms: | CHEMBL3775005 | US10273244, Example 30 | US10584135, Example 30 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H27FN6OS |
|---|
| Mol. Mass. | 442.553 |
|---|
| SMILES | Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2cccc(F)c2)n1C |
|---|
| Structure | 
|
|---|
Search and Browse
