| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM438874 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competitive Displacement Assay |
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| Ki | <1±n/a nM |
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| Citation |  Wynn, TA; Alvarez, JC; Moustakas, DT; Haeberlein, M; Pennington, LD Compounds for the treatment of pain US Patent US10604489 Publication Date 3/31/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM438874 |
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| n/a |
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| Name | BDBM438874 |
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| Synonyms: | 5-((1R,5S,9r)-3-(cyclopropylmethyl)-9-methoxy-3-azabicyclo[3.3.1]nonan-9-yl)thiophene-2-carboxamide hydrochloride | US10604489, Compound 36 | US11180455, Compound 36 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26N2O2S |
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| Mol. Mass. | 334.476 |
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| SMILES | COC1(C2CCCC1CN(CC1CC1)C2)c1ccc(s1)C(N)=O |TLB:10:9:2:5.4.6,15:2:5.4.6:8.14.9,THB:1:2:5.4.6:8.14.9| |
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| Structure | 
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