| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM439007 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competitive Displacement Assay |
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| Ki | <1±n/a nM |
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| Citation |  Wynn, TA; Alvarez, JC; Moustakas, DT; Haeberlein, M; Pennington, LD Compounds for the treatment of pain US Patent US10604489 Publication Date 3/31/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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|
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| BDBM439007 |
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| n/a |
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| Name | BDBM439007 |
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| Synonyms: | US10604489, Compound 197 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27F2N3O2 |
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| Mol. Mass. | 391.4548 |
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| SMILES | COC1(C2CCCC1CN(C2)[C@@H]1C[C@H]2[C@@H](C1)C2(F)F)c1ccnc(c1)C(N)=O |r,TLB:11:9:2:5.4.6,19:2:9.8.10:5.4.6,THB:1:2:9.8.10:5.4.6| |
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| Structure | 
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