| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase, cytosolic |
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| Ligand | BDBM448320 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | >10000±n/a nM |
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| Citation |  Eckhardt, M; Gollner, A; Langkopf, E; Wagner, H; Wiedenmayer, D Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors US Patent US10695334 Publication Date 6/30/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidine kinase, cytosolic |
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| Name: | Thymidine kinase, cytosolic |
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| Synonyms: | KITH_HUMAN | TK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25476.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1333884 |
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| Residue: | 234 |
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| Sequence: | MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
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| BDBM448320 |
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| n/a |
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| Name | BDBM448320 |
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| Synonyms: | 1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-methylpyridin-3-yl)methyl]-N-{3-methyl-1H,4H,5H,6H-cyclopenta[c]pyrazol-6-yl}-1H-pyrazole-4-carboxamide | US10695334, Example 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27N7O |
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| Mol. Mass. | 417.5068 |
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| SMILES | Cc1n[nH]c2C(CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC3CC3C2)c1 |
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| Structure | 
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