| Reaction Details |
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 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
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| Ligand | BDBM450243 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays |
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| EC50 | 61.0±n/a nM |
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| Citation |  Shirude, PS; Baligar, V; Seshadri, B; Chattopadhyay, AK; Wurtz, NR; Kick, EK Phenylpyrrolidinone formyl peptide 2 receptor agonists US Patent US10676431 Publication Date 6/9/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| fMet-Leu-Phe receptor |
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| Name: | fMet-Leu-Phe receptor |
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| Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38456.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4503779 |
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| Residue: | 350 |
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| Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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| BDBM450243 |
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| n/a |
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| Name | BDBM450243 |
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| Synonyms: | US10676431, Example 8 | US11117861, Example 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H17ClF2N4O2 |
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| Mol. Mass. | 466.867 |
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| SMILES | Fc1c(F)c(ccc1N1CC[C@@H](NC(=O)Nc2ccc(Cl)cc2)C1=O)-c1ccccc1C#N |r| |
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| Structure | 
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