| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM179891 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Opioid Receptor Binding Assay |
|---|
| Ki | 0.370±n/a nM |
|---|
| Citation |  Blumberg, LC; Deaver, DR; Eyerman, DJ; Wynn, TA Morphan and morphinan analogues, and methods of use US Patent US10752592 Publication Date 8/25/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44789.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35372 |
|---|
| Residue: | 400 |
|---|
| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM179891 |
|---|
| n/a |
|---|
| Name | BDBM179891 |
|---|
| Synonyms: | US10287250, Compound C.9 | US10752592, Compound TABLE C.-5 | US9133125, Table C, Compound 9 | US9656961, Example 00159 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H37N3O4 |
|---|
| Mol. Mass. | 551.6753 |
|---|
| SMILES | Oc1c(ccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC(=O)CC[C@@]34O)c12)C(=O)NCCc1ccc(cc1)-c1cccnc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
