Reaction Details | |||
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Target | N-formyl peptide receptor 2 | ||
Ligand | BDBM350523 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | FLIPR | ||
EC50 | 363±n/a nM | ||
Citation | Viswanath, V; Beard, RL; Donello, JE; Hsia, E Use of agonists of formyl peptide receptor 2 for treating dermatological diseases US Patent US10799518 Publication Date 10/13/2020 | ||
More Info.: | Get all data from this article, Assay Method | ||
N-formyl peptide receptor 2 | |||
Name: | N-formyl peptide receptor 2 | ||
Synonyms: | ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 38968.35 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P25090 | ||
Residue: | 351 | ||
Sequence: |
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BDBM350523 | |||
n/a | |||
Name | BDBM350523 | ||
Synonyms: | 1-(8-methyl-2,4-dioxo-1,3- diazaspiro[4,5]decan-3-yl)-3- (p-tolypurea | US10208071, Table 2.4 | US10434112, Table 2.4 | US10799518, Structure TABLE 2.4 | ||
Type | Small organic molecule | ||
Emp. Form. | C17H22N4O3 | ||
Mol. Mass. | 330.3816 | ||
SMILES | CC1CCC2(CC1)NC(=O)N(NC(=O)Nc1ccc(C)cc1)C2=O |(-6.85,-3.59,;-5.76,-2.5,;-6.16,-1.01,;-5.07,.08,;-3.58,-.32,;-3.19,-1.81,;-4.27,-2.9,;-4.06,1.14,;-2.81,2.05,;-2.81,3.59,;-1.57,1.14,;-.08,1.54,;1.01,.45,;.61,-1.03,;2.5,.85,;3.58,-.24,;3.19,-1.73,;4.27,-2.81,;5.76,-2.42,;6.85,-3.5,;6.16,-.93,;5.07,.16,;-2.04,-.32,;-1.27,-1.66,)| | ||
Structure |