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TargetN-formyl peptide receptor 2
LigandBDBM350523
Substrate/Competitorn/a
Meas. Tech.FLIPR
EC50 363±n/a nM
Citation Viswanath, VBeard, RLDonello, JEHsia, E Use of agonists of formyl peptide receptor 2 for treating dermatological diseases US Patent US10799518 Publication Date 10/13/2020
More Info.:Get all data from this article,  Assay Method
 
N-formyl peptide receptor 2
Name:N-formyl peptide receptor 2
Synonyms:ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:38968.35
Organism:Homo sapiens (Human)
Description:P25090
Residue:351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
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  Blast E-value cutoff:
BDBM350523
n/a
NameBDBM350523
Synonyms:1-(8-methyl-2,4-dioxo-1,3- diazaspiro[4,5]decan-3-yl)-3- (p-tolypurea | US10208071, Table 2.4 | US10434112, Table 2.4 | US10799518, Structure TABLE 2.4
TypeSmall organic molecule
Emp. Form.C17H22N4O3
Mol. Mass.330.3816
SMILESCC1CCC2(CC1)NC(=O)N(NC(=O)Nc1ccc(C)cc1)C2=O |(-6.85,-3.59,;-5.76,-2.5,;-6.16,-1.01,;-5.07,.08,;-3.58,-.32,;-3.19,-1.81,;-4.27,-2.9,;-4.06,1.14,;-2.81,2.05,;-2.81,3.59,;-1.57,1.14,;-.08,1.54,;1.01,.45,;.61,-1.03,;2.5,.85,;3.58,-.24,;3.19,-1.73,;4.27,-2.81,;5.76,-2.42,;6.85,-3.5,;6.16,-.93,;5.07,.16,;-2.04,-.32,;-1.27,-1.66,)|
Structure
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