| Reaction Details |
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 | Report a problem with these data |
| Target | N-formyl peptide receptor 2 |
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| Ligand | BDBM350538 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FLIPR |
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| EC50 | 395000±n/a nM |
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| Citation |  Viswanath, V; Beard, RL; Donello, JE; Hsia, E Use of agonists of formyl peptide receptor 2 for treating dermatological diseases US Patent US10799518 Publication Date 10/13/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| N-formyl peptide receptor 2 |
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| Name: | N-formyl peptide receptor 2 |
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| Synonyms: | ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38968.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25090 |
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| Residue: | 351 |
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| Sequence: | METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
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|
|
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| BDBM350538 |
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| n/a |
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| Name | BDBM350538 |
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| Synonyms: | N-(4-bromophenyl)-1,3,3a,4,7,7a- hexahydro-1,3-dioxo-2H-isoindole-2- acetamide | US10208071, Table 3.14 | US10434112, Table 3.14 | US10799518, Structure TABLE 3.14 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15BrN2O3 |
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| Mol. Mass. | 363.206 |
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| SMILES | Brc1ccc(NC(=O)CN2C(=O)C3CC=CCC3C2=O)cc1 |c:14| |
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| Structure | 
|
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