| Reaction Details |
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 | Report a problem with these data |
| Target | N-formyl peptide receptor 2 |
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| Ligand | BDBM350553 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FLIPR |
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| EC50 | 0.600±n/a nM |
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| Citation |  Viswanath, V; Beard, RL; Donello, JE; Hsia, E Use of agonists of formyl peptide receptor 2 for treating dermatological diseases US Patent US10799518 Publication Date 10/13/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| N-formyl peptide receptor 2 |
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| Name: | N-formyl peptide receptor 2 |
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| Synonyms: | ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38968.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25090 |
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| Residue: | 351 |
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| Sequence: | METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
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| BDBM350553 |
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| n/a |
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| Name | BDBM350553 |
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| Synonyms: | 3-[(4- iodophenyl)carbamoyl] spiro[bicyclo[2.2.1]heptane- 7,1'-cyclopropane]-2-carboxylic acid | US10208071, Compound 15 | US10434112, Compound 15 | US10799518, Compound 15 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18INO3 |
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| Mol. Mass. | 411.2342 |
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| SMILES | OC(=O)C1C2CCC(C1C(=O)Nc1ccc(I)cc1)C21CC1 |TLB:9:8:6.5:19,THB:1:3:6.5:19| |
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| Structure | 
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