| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM466576 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Evaluation of Binding Activity to Human 5-HT1A Receptor, Human D4 Receptor, and Human D2 Receptor |
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| IC50 | 14.0±n/a nM |
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| Citation |  Yoshinaga, H; Uemachi, H; Ohno, T; Besnard, J 2,6-disubstituted pyridine derivative US Patent US10800755 Publication Date 10/13/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM466576 |
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| n/a |
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| Name | BDBM466576 |
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| Synonyms: | 2,2-Dimethyl-N-[2-(6-methyl-3′,6′-dihydro[2,4′-bipyridin]-1′ (2′H)-yl)ethyl]propanamide | US10800755, Example 30 | US11014905, Example 30 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H27N3O |
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| Mol. Mass. | 301.4265 |
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| SMILES | Cc1cccc(n1)C1=CCN(CCNC(=O)C(C)(C)C)CC1 |t:8| |
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| Structure | 
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