| Reaction Details |
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 | Report a problem with these data |
| Target | Histone acetyltransferase KAT7 [325-611] |
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| Ligand | BDBM653701 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Acetyltransferase Biochemical Assay |
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| IC50 | 1090±n/a nM |
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| Citation |  Stupple, PA; Lagiakos, HR; Foitzik, RC; Camerino, MA; Nikolakopoulos, G; Bozikis, YE; Kersten, WJ; Walker, SR; Hubert, JG Compounds US Patent US11911372 Publication Date 2/27/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone acetyltransferase KAT7 [325-611] |
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| Name: | Histone acetyltransferase KAT7 |
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| Synonyms: | 2.3.1.48 | HBO1 | HBOa | Histone acetyltransferase KAT7 | Histone acetyltransferase binding to ORC1 | KAT7 | KAT7_HUMAN | Lysine acetyltransferase 7 | MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2 | MYST-2 | MYST2 | Synonyms=HBO1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 70665.79 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_116753 |
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| Residue: | 611 |
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| Sequence: | MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVR
NLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTAD
HDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYN
FNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECKVRAQSRDKQIEERMLSHRQ
DDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLEN
LTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYA
RLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQN
LCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQ
YMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEIS
IKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDP
SCLKWTPPKGT
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| BDBM653701 |
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| n/a |
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| Name | BDBM653701 |
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| Synonyms: | US11911372, Example 124 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N2O6S |
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| Mol. Mass. | 466.506 |
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| SMILES | COc1ccccc1-c1cc(NS(=O)(=O)c2c(OC)cccc2OCc2ccccc2)no1 |
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| Structure | 
|
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