| Reaction Details |
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 | Report a problem with these data |
| Target | Pantetheinase |
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| Ligand | BDBM475869 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| IC50 | 0.100±n/a nM |
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| Citation |  Godbout, C; Fleck, MT; Koolman, HF Heteroaromatic compounds as Vanin inhibitors US Patent US10864201 Publication Date 12/15/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Pantetheinase |
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| Name: | Pantetheinase |
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| Synonyms: | Pantetheine hydrolase | Tiff66 | VNN1 | VNN1_HUMAN | Vanin-1 | Vascular non-inflammatory molecule 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57002.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O95497 |
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| Residue: | 513 |
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| Sequence: | MTTQLPAYVAILLFYVSRASCQDTFTAAVYEHAAILPNATLTPVSREEALALMNRNLDIL
EGAITSAADQGAHIIVTPEDAIYGWNFNRDSLYPYLEDIPDPEVNWIPCNNRNRFGQTPV
QERLSCLAKNNSIYVVANIGDKKPCDTSDPQCPPDGRYQYNTDVVFDSQGKLVARYHKQN
LFMGENQFNVPKEPEIVTFNTTFGSFGIFTCFDILFHDPAVTLVKDFHVDTIVFPTAWMN
VLPHLSAVEFHSAWAMGMRVNFLASNIHYPSKKMTGSGIYAPNSSRAFHYDMKTEEGKLL
LSQLDSHPSHSAVVNWTSYASSIEALSSGNKEFKGTVFFDEFTFVKLTGVAGNYTVCQKD
LCCHLSYKMSENIPNEVYALGAFDGLHTVEGRYYLQICTLLKCKTTNLNTCGDSAETAST
RFEMFSLSGTFGTQYVFPEVLLSENQLAPGEFQVSTDGRLFSLKPTSGPVLTVTLFGRLY
EKDWASNASSGLTAQARIIMLIVIAPIVCSLSW
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| BDBM475869 |
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| n/a |
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| Name | BDBM475869 |
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| Synonyms: | US10864201, Ex. 7.1 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25ClN4O2 |
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| Mol. Mass. | 424.923 |
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| SMILES | C[C@@]1(Cc2cc(cnc2N1)C(=O)N1CC[C@@H](C1)N1CCCC1=O)c1cccc(Cl)c1 |r| |
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| Structure | 
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