| Reaction Details |
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 | Report a problem with these data |
| Target | Protein M2-1 |
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| Ligand | BDBM301510 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Antiviral Activity |
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| EC50 | 7762±n/a nM |
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| Citation |  Tahari, A; Vendeville, SM; Jonckers, TH; Raboisson, PJ; Demin, SD; Hu, L Piperidine substituted tricyclic pyrazolo[1,5-a]pyrimidine derivatives with inhibitory activity on the replication of the respiratory syncytial virus (RSV) US Patent US10131673 Publication Date 11/20/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein M2-1 |
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| Name: | Protein M2-1 |
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| Synonyms: | Envelope-associated 22 kDa protein | M2-1 | M21_HRSVA | Matrix M2-1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 22163.59 |
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| Organism: | Human respiratory syncytial virus A (strain A2) |
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| Description: | P04545 |
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| Residue: | 194 |
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| Sequence: | MSRRNPCKFEIRGHCLNGKRCHFSHNYFEWPPHALLVRQNFMLNRILKSMDKSIDTLSEI
SGAAELDRTEEYALGVVGVLESYIGSINNITKQSACVAMSKLLTELNSDDIKKLRDNEEL
NSPKIRVYNTVISYIESNRKNNKQTIHLLKRLPADVLKKTIKNTLDIHKSITINNPKEST
VSDTNDHAKNNDTT
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| BDBM301510 |
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| n/a |
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| Name | BDBM301510 |
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| Synonyms: | US10131673, Compound P37 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H28N6 |
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| Mol. Mass. | 412.53 |
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| SMILES | Cc1cccc2ncnc(N3CCCC[C@@H]3c3cc4nc5CCCCc5c(C)n4n3)c12 |r| |
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| Structure | 
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