| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glycogen synthase kinase-3 beta [7-25] |
|---|
| Ligand | BDBM7848 |
|---|
| Substrate/Competitor | GSK-3 Peptide Substrate |
|---|
| Meas. Tech. | Kinase Inhibition Assay |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | 8500±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Martinez, A; Alonso, M; Castro, A; Dorronsoro, I; Gelpi, JL; Luque, FJ; Perez, C; Moreno, FJ SAR and 3D-QSAR studies on thiadiazolidinone derivatives: exploration of structural requirements for glycogen synthase kinase 3 inhibitors. J Med Chem48:7103-12 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Glycogen synthase kinase-3 beta [7-25] |
|---|
| Name: | Glycogen synthase kinase-3 beta [7-25] |
|---|
| Synonyms: | G1T8E2_RABIT | GSK-3, beta | GSK3B | Glycogen Synthase Kinase-3, beta |
|---|
| Type: | Enzyme fragment |
|---|
| Mol. Mass.: | 1972.14 |
|---|
| Organism: | Oryctolagus cuniculus (rabbit) |
|---|
| Description: | Glycogen Synthase Kinase-3 is the beta isoform of the rabbit enzyme produced in E.coli..
Only partial sequence is available. |
|---|
| Residue: | 19 |
|---|
| Sequence: | |
|---|
| BDBM7848 |
|---|
| GSK-3 Peptide Substrate |
|---|
| Name: | GSK-3 Peptide Substrate |
|---|
| Synonyms: | GS-1 Peptide | Phospho-GS2 Substrate Peptide |
|---|
| Type: | Peptide |
|---|
| Mol. Mass.: | 3045.17 |
|---|
| Organism: | n/a |
|---|
| Description: | n/a |
|---|
| Residue: | 27 |
|---|
| Sequence: | YRRAAVPPSPSLSRHSSPHQS(PO4)EDEEE
|
|
|
|---|
Search and Browse
