Reaction Details | |||
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Target | Tyrosine-protein phosphatase non-receptor type 11 | ||
Ligand | BDBM497106 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Biochemical Assay | ||
IC50 | 1.40±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Tyrosine-protein phosphatase non-receptor type 11 | |||
Name: | Tyrosine-protein phosphatase non-receptor type 11 | ||
Synonyms: | 3.1.3.48 | PTN11_HUMAN | PTP-1D | PTP-2C | PTP2C | PTPN11 | Protein Tyrosine Phosphatase PPN11/Shp2 | Protein tyrosine phosphatase (PTP) Shp2 | Protein-Tyrosine Phosphatase SHP-2 | Protein-tyrosine phosphatase 1D | Protein-tyrosine phosphatase 2C | SH-PTP2 | SH-PTP3 | SHP-2 | SHP2 | SHPTP2 | Src homology phosphatase 2 (SHP-2) | Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) | Tyrosine-protein phosphatase non-receptor type 11 (SHP-2) | Tyrosine-protein phosphatase non-receptor type 11 (SHP2) | ||
Type: | Protein phosphatase | ||
Mol. Mass.: | 68443.59 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q06124 | ||
Residue: | 593 | ||
Sequence: |
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BDBM497106 | |||
n/a | |||
Name | BDBM497106 | ||
Synonyms: | US11001561, Compound 81b | US11702392, Compound 81a | ||
Type | Small organic molecule | ||
Emp. Form. | C24H24Cl2N4O2 | ||
Mol. Mass. | 471.379 | ||
SMILES | Cc1nc(N2CCC3(CC2)Oc2ccccc2[C@H]3N)c(C)c(=O)n1-c1cccc(Cl)c1Cl |wU:17.20,(-7.45,-1.1,;-6.68,-2.44,;-5.14,-2.44,;-4.37,-3.77,;-2.83,-3.77,;-2.06,-5.1,;-.52,-5.1,;.25,-3.77,;-.52,-2.44,;-2.06,-2.44,;1.16,-2.53,;2.62,-3,;3.96,-2.23,;5.29,-3,;5.29,-4.54,;3.96,-5.31,;2.62,-4.54,;1.16,-5.02,;.68,-6.48,;-5.14,-5.1,;-4.37,-6.44,;-6.68,-5.1,;-7.45,-6.44,;-7.45,-3.77,;-8.99,-3.77,;-9.76,-2.44,;-11.3,-2.44,;-12.07,-3.77,;-11.3,-5.1,;-12.07,-6.44,;-9.76,-5.1,;-8.99,-6.44,)| | ||
Structure | ![]() |