| Reaction Details |
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 | Report a problem with these data |
| Target | Dihydrofolate reductase |
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| Ligand | BDBM50461737 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TBD |
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| IC50 | 160±n/a nM |
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| Citation |  Gangjee, A Pyrimidine compounds and pyrimido indole compounds and methods of use US Patent US11001595 Publication Date 5/11/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Dihydrofolate reductase |
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| Name: | Dihydrofolate reductase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 23415.37 |
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| Organism: | Human pneumocystis pneumonia agent |
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| Description: | A0A0W4ZHR8 |
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| Residue: | 206 |
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| Sequence: | MDWQKSLTLIVALTLSRGIGLKNDLPWKLKSDMMFFSRVTSGLLVTRSTGQMNVVLMGRK
TWESLPAHSRPLKNRINVVISRQEVLDLGGGAYHARSLDDALALLSQIYDSTSKIQLNRV
FVIGGGELYKAAMEHSRLNRIIATVIHNEVDCDVFFPIDFRSSQSCLPWRKQDHSVLEAW
VGSKVPQGKINENGFIYEFEMWIRDI
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| BDBM50461737 |
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| n/a |
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| Name | BDBM50461737 |
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| Synonyms: | CHEMBL4227977 | US11001595, Compound 7 | US11111252, Compound 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17N5OS |
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| Mol. Mass. | 315.393 |
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| SMILES | COc1cccc(Sc2c(C)c3c(N)nc(N)nc3n2C)c1 |
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| Structure | 
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