| Reaction Details |
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 | Report a problem with these data |
| Target | N-formyl peptide receptor 2 |
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| Ligand | BDBM497412 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | cAMP Assay |
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| EC50 | 18.0±n/a nM |
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| Citation |  Shirude, PS; Chattopadhyay, AK; Rachamreddy, C; Wurtz, NR; Kick, EK Piperidinone formyl peptide 2 receptor agonists US Patent US11008301 Publication Date 5/18/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| N-formyl peptide receptor 2 |
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| Name: | N-formyl peptide receptor 2 |
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| Synonyms: | ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38968.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25090 |
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| Residue: | 351 |
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| Sequence: | METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
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| BDBM497412 |
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| n/a |
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| Name | BDBM497412 |
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| Synonyms: | US11008301, Example 104 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26F3N5O3 |
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| Mol. Mass. | 489.4901 |
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| SMILES | FC(F)(F)c1ccc(NC(=O)N[C@@H]2CCCN(C2=O)c2ccc(nc2)N2C[C@@H]3CC[C@H](C2)O3)cc1 |r| |
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| Structure | 
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