| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM506801 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | 5-HT2C Binding Assay |
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| Ki | 13±n/a nM |
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| Citation |  Duggan, ME; Edgar, DM Piperazine substituted azapine derivatives and uses thereof US Patent US11046651 Publication Date 6/29/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT-1C | 5-HT-2C | 5-HT1C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 51836.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28335 |
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| Residue: | 458 |
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| Sequence: | MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA
ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV
LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM
QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC
SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN
EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
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| BDBM506801 |
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| n/a |
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| Name | BDBM506801 |
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| Synonyms: | US11046651, Compound 34 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26ClN3O3 |
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| Mol. Mass. | 427.924 |
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| SMILES | Cc1ccc2Oc3ccc(Cl)cc3N=C(N3CCN(CC(C)(C)C(O)=O)CC3)c2c1 |t:14| |
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| Structure | 
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