| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 6 |
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| Ligand | BDBM50544441 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 33800±6800 nM |
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| Citation |  Zhang, Z; Ruddraraju, KV N-aryl oxamic acids US Patent US11192850 Publication Date 12/7/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein phosphatase non-receptor type 6 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 6 |
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| Synonyms: | HCP | PTN6_HUMAN | PTP1C | PTPN6 | Protein tyrosine phosphatase SHP-1 (SHP-1) | Protein-tyrosine phosphatase 1C | Protein-tyrosine phosphatase SHP-1 | Src homology phosphatase 1 (SHP-1) | Tyrosine-protein phosphatase non-receptor type 6 | Tyrosine-protein phosphatase non-receptor type 6 (SHP1) |
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| Type: | Protein |
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| Mol. Mass.: | 67570.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29350 |
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| Residue: | 595 |
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| Sequence: | MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDF
YDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQA
ETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGG
LETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSD
YINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNK
CVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDC
DIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNIT
YPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
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| BDBM50544441 |
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| n/a |
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| Name | BDBM50544441 |
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| Synonyms: | CHEMBL4637373 | US11192850, Entry 4u |
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| Type | Small organic molecule |
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| Emp. Form. | C17H9BrF3NO3 |
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| Mol. Mass. | 412.157 |
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| SMILES | OC(=O)C(=O)Nc1ccc(cc1)C#Cc1ccc(cc1Br)C(F)(F)F |
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| Structure | 
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