| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lysocardiolipin acyltransferase 1 |
|---|
| Ligand | BDBM532078 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro Acyltransferase Assays |
|---|
| IC50 | <10.00±n/a nM |
|---|
| Citation |  Shi, Y; Che, D; Baell, J; Liu, X; Fu, J Compounds useful as inhibitors of ALCAT 1 US Patent US11208404 Publication Date 12/28/2021 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lysocardiolipin acyltransferase 1 |
|---|
| Name: | Lysocardiolipin acyltransferase 1 |
|---|
| Synonyms: | 1-AGP acyltransferase 8 | 1-AGPAT 8 | 1-acylglycerol-3-phosphate O-acyltransferase 8 | AGPAT8 | ALCAT1 | Acyl-CoA:lysocardiolipin acyltransferase 1 | LCLAT1 | LCLT1_HUMAN | LYCAT |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 48934.23 |
|---|
| Organism: | Human |
|---|
| Description: | Q6UWP7 |
|---|
| Residue: | 414 |
|---|
| Sequence: | MHSRGREIVVLLNPWSINEAVSSYCTYFIKQDSKSFGIMVSWKGIYFILTLFWGSFFGSI
FMLSPFLPLMFVNPSWYRWINNRLVATWLTLPVALLETMFGVKVIITGDAFVPGERSVII
MNHRTRMDWMFLWNCLMRYSYLRLEKICLKASLKGVPGFGWAMQAAAYIFIHRKWKDDKS
HFEDMIDYFCDIHEPLQLLIFPEGTDLTENSKSRSNAFAEKNGLQKYEYVLHPRTTGFTF
VVDRLREGKNLDAVHDITVAYPHNIPQSEKHLLQGDFPREIHFHVHRYPIDTLPTSKEDL
QLWCHKRWEEKEERLRSFYQGEKNFYFTGQSVIPPCKSELRVLVVKLLSILYWTLFSPAM
CLLIYLYSLVKWYFIITIVIFVLQERIFGGLEIIELACYRLLHKQPHLNSKKNE
|
|
|
|---|
| BDBM532078 |
|---|
| n/a |
|---|
| Name | BDBM532078 |
|---|
| Synonyms: | US11208404, Compound 222 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H20FN3O4 |
|---|
| Mol. Mass. | 421.421 |
|---|
| SMILES | CCOc1ccc(CC)cc1C(=O)Nc1cc(ccc1F)-c1nnc(o1)-c1ccco1 |
|---|
| Structure | 
|
|---|
Search and Browse
