| Reaction Details |
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 | Report a problem with these data |
| Target | Histone acetyltransferase KAT8 |
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| Ligand | BDBM580678 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kat8 Assay |
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| Ki | 100.0±n/a nM |
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| Citation |  Bozikis, YE; Camerino, MA; Kung, P; Stupple, PA; Sutton, SC Benzisoxazole sulfonamide derivatives US Patent US11492346 Publication Date 11/8/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone acetyltransferase KAT8 |
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| Name: | Histone acetyltransferase KAT8 |
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| Synonyms: | KAT8 | KAT8_HUMAN | Lysine acetyltransferase 8 | MOF | MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1 | MYST-1 | MYST1 | hMOF |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52413.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_796800 |
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| Residue: | 458 |
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| Sequence: | MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGET
YLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQ
KNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVD
KIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEI
YRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVG
YFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLS
YRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPK
LVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK
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| BDBM580678 |
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| n/a |
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| Name | BDBM580678 |
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| Synonyms: | US11492346, Example 18 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N4O5S |
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| Mol. Mass. | 456.515 |
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| SMILES | COc1ccc(cc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12)C(C)C |
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| Structure | 
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