Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine/threonine-protein kinase pim-1 | ||
| Ligand | BDBM602107 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Pim-1 Inhibitory Activity Assay | ||
| Ki | 0.006±n/a nM | ||
| Citation |  Inoue, M; Ogoshi, Y; Furukawa, T; Machida, T; Mitani, I; Harada, K; Nakagawa, Y; Yamaoka, N Tetrahydrobenzofurodiazepinone compound and pharmaceutical use thereof US Patent US11643417 Publication Date 5/9/2023 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine/threonine-protein kinase pim-1 | |||
| Name: | Serine/threonine-protein kinase pim-1 | ||
| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) | ||
| Type: | Protein | ||
| Mol. Mass.: | 35681.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P11309 | ||
| Residue: | 313 | ||
| Sequence: |
| ||
| BDBM602107 | |||
| n/a | |||
| Name | BDBM602107 | ||
| Synonyms: | US11643417, Ex. No. 120 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H23F5N2O4 | ||
| Mol. Mass. | 462.4103 | ||
| SMILES | OCC1(O)CCC(CC1)C(F)(F)CN1CCNC(=O)c2oc3ccc(cc3c12)C(F)(F)F |(7.13,.13,;5.59,.13,;4.82,1.46,;6.31,1.86,;3.67,.45,;2.21,.95,;1.91,2.46,;3.07,3.47,;4.53,2.98,;.45,2.96,;-.56,4.12,;.95,4.42,;-.71,1.94,;-2.16,2.44,;-2.35,3.97,;-3.66,4.78,;-5.11,4.26,;-5.61,2.8,;-7.13,2.62,;-4.78,1.51,;-5.4,.1,;-4.26,-.93,;-4.26,-2.47,;-2.92,-3.24,;-1.59,-2.47,;-1.59,-.93,;-2.92,-.16,;-3.25,1.35,;-.26,-3.24,;1.08,-2.47,;-.26,-4.78,;1.08,-4.01,)| | ||
| Structure | 
| ||