| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-7 |
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| Ligand | BDBM604956 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding to Nicotinic Receptor Subtypes |
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| Ki | 10890±n/a nM |
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| Citation |  Gallagher, TC; Rego Campello, H 4-substitued cytisine analogues US Patent US11667638 Publication Date 6/6/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuronal acetylcholine receptor subunit alpha-7 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-7 |
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| Synonyms: | ACHA7_HUMAN | CHRNA7 | Cholinergic, Nicotinic Alpha7 | NACHRA7 | Neuronal acetylcholine receptor protein alpha-7 subunit | Neuronal acetylcholine receptor subunit alpha-7 (nAChR-alpha 7) | Nicotinic acetylcholine receptor alpha-7 (alpha7 nAChR) |
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| Type: | n/a |
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| Mol. Mass.: | 56448.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | CHRNA7 (NACHRA7) |
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| Residue: | 502 |
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| Sequence: | MRCSPGGVWLALAASLLHVSLQGEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLL
QIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADE
RFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDL
QMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIP
CVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFAST
MIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHK
QRRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHL
LHGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTI
ICTIGILMSAPNFVEAVSKDFA
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| BDBM604956 |
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| n/a |
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| Name | BDBM604956 |
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| Synonyms: | US11667638, Example 74 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13F5N2O |
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| Mol. Mass. | 356.2899 |
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| SMILES | Fc1c(F)c(F)c(c(F)c1F)-c1cc2[C@@H]3CNCC(C3)Cn2c(=O)c1 |r| |
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| Structure | 
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