| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Programmed cell death 1 ligand 1 |
|---|
| Ligand | BDBM482370 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme-Linked Immunosorbent Assay ELISA |
|---|
| IC50 | <5±n/a nM |
|---|
| Citation |  Lange, C; Malathong, V; Mali, VR; McMahon, J; McMurtrie, DJ; Punna, S; Roth, HS; Singh, R; Wang, Y; Yang, J; Zhang, P Immunomodulator compounds US Patent US11708326 Publication Date 7/25/2023 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Programmed cell death 1 ligand 1 |
|---|
| Name: | Programmed cell death 1 ligand 1 |
|---|
| Synonyms: | B7 homolog 1 | B7-H1 | B7H1 | B7H1 | CD274 | CD_antigen=CD274 | PD-L1 | PD1L1_HUMAN | PDCD1 ligand 1 | PDCD1L1 | PDCD1LG1 | PDL1 | Programmed cell death 1 ligand 1 | Programmed death ligand 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 33278.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_109807 |
|---|
| Residue: | 290 |
|---|
| Sequence: | MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEME
DKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGG
ADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTT
TTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTH
LVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
|
|
|
|---|
| BDBM482370 |
|---|
| n/a |
|---|
| Name | BDBM482370 |
|---|
| Synonyms: | US10919852, Compound TABLE 1.69 | US11708326, Compound TABLE 1.69 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C44H51ClN4O5 |
|---|
| Mol. Mass. | 751.353 |
|---|
| SMILES | Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CCC(C)(O)CC2)cc1Cl |r| |
|---|
| Structure | 
|
|---|
Search and Browse
