| Reaction Details |
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 | Report a problem with these data |
| Target | Transcriptional enhancer factor TEF-5 |
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| Ligand | BDBM626328 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HTRF Assay |
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| IC50 | 11000±n/a nM |
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| Citation |  Zbieg, JR; Beroza, PP Therapeutic compounds and methods of use US Patent US11787775 Publication Date 10/17/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Transcriptional enhancer factor TEF-5 |
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| Name: | Transcriptional enhancer factor TEF-5 |
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| Synonyms: | DTEF-1 | TEA domain family member 3 | TEAD-3 | TEAD3 | TEAD3_HUMAN | TEAD5 | TEF5 | Transcriptional enhancer factor TEF-5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48683.38 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119185 |
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| Residue: | 435 |
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| Sequence: | MASNSWNASSSPGEAREDGPEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL
SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKD
KALQSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKP
FAQPAYPIQPPLPPTLSSYEPLAPLPSAAASVPVWQDRTIASSRLRLLEYSAFMEVQRDP
DTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFW
ADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVY
RIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVST
SEHGAQHHVYKLVKD
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|
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| BDBM626328 |
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| n/a |
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| Name | BDBM626328 |
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| Synonyms: | 2-[[[4-(hydroxymethyl)-7-(4- isopropylphenyl)-2,3- dihydrobenzofuran-5- yl]amino]methyl]prop-2-enamide | US11787775, Compound 13 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26N2O3 |
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| Mol. Mass. | 366.4534 |
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| SMILES | CC(C)c1ccc(cc1)-c1cc(NCC(=C)C(N)=O)c(CO)c2CCOc12 |
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| Structure | 
|
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