Ki Summary

Reaction Details

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Target

FABP3 protein

Ligand

BDBM635764

Substrate/Competitor

n/a

Meas. Tech.

FABP3, FABP5, and FABP7 Binding Assay

7670±710 nM

Citation

Ojima, I; Kaczocha, M; Awwa, M; Pepe, A TRUXILLIC ACID MONOESTER-DERIVATIVES AS SELECTIVE FABP5 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF US Patent US20230365488 Publication Date 11/16/2023

More Info.:

Get all data from this article, Assay Method

FABP3 protein

Name:

FABP3 protein

Synonyms:

n/a

Type:

Protein

Mol. Mass.:

14830.30

Organism:

Human

Description:

Q6IBD7

Residue:

133

Sequence:

MADAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN
TEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTH
GTAVCTRTYEKEA

BDBM635764

n/a

Name

BDBM635764

Synonyms:

US20230365488, Compound 1u

Type

Small organic molecule

Emp. Form.

C33H27NO5

Mol. Mass.

517.5712

SMILES

OC(=O)[C@H]1[C@@H]([C@@H]([C@H]1c1ccccc1)C(=O)Oc1cccc(c1)-c1ccc2CCC(=O)Nc2c1)c1ccccc1 |r,wU:4.37,5.14,wD:3.2,6.7,(-5.67,-4.73,;-6.07,-3.24,;-7.56,-2.84,;-4.98,-2.15,;-3.44,-2.15,;-3.44,-.61,;-4.98,-.61,;-6.07,.48,;-5.67,1.97,;-6.76,3.05,;-8.25,2.66,;-8.65,1.17,;-7.56,.08,;-2.35,.48,;-.86,.08,;-2.75,1.97,;-1.66,3.05,;-2.06,4.54,;-.97,5.63,;.52,5.23,;.92,3.75,;-.17,2.66,;2.4,3.35,;2.8,1.86,;4.29,1.46,;5.38,2.55,;6.87,2.15,;7.95,3.24,;7.56,4.73,;8.65,5.82,;6.07,5.13,;4.98,4.04,;3.49,4.44,;-2.35,-3.24,;-2.75,-4.73,;-1.66,-5.82,;-.17,-5.42,;.23,-3.93,;-.86,-2.84,)|

Structure