Reaction Details |
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Target | Sigma intracellular receptor 2 |
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Ligand | BDBM321276 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Binding Assay to Sigma Receptors |
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Ki | 59.0±n/a nM |
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Citation | Melnyk, P; Vermersch, P; Carato, P; Oxombre-Vanteghem, B; Zephir, H; Donnier-Marechal, M Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases US Patent US10179761 Publication Date 1/15/2019 |
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More Info.: | Get all data from this article, Assay Method |
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Sigma intracellular receptor 2 |
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Name: | Sigma intracellular receptor 2 |
Synonyms: | MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97 |
Type: | Protein |
Mol. Mass.: | 20857.20 |
Organism: | Homo sapiens (Human) |
Description: | Q5BJF2 |
Residue: | 176 |
Sequence: | MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
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BDBM321276 |
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n/a |
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Name | BDBM321276 |
Synonyms: | N-[3-(benzylmethylamino)propyl]-3,4-dichlorobenzamide | US10179761, Compound 3.1.25 |
Type | Small organic molecule |
Emp. Form. | C18H20Cl2N2O |
Mol. Mass. | 351.27 |
SMILES | CN(CCCNC(=O)c1ccc(Cl)c(Cl)c1)Cc1ccccc1 |
Structure |
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