| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
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| Ligand | BDBM323223 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Transactivation Assay |
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| EC50 | 4000±n/a nM |
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| Citation |  Bouix-Peter, C; Suzuki, I; Rodeville, N; Mauvais, P; Pascal, J Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics US Patent US9630949 Publication Date 4/25/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 4 |
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| Name: | Melanocortin receptor 4 |
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| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36949.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32245 |
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| Residue: | 332 |
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| Sequence: | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
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| BDBM323223 |
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| n/a |
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| Name | BDBM323223 |
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| Synonyms: | N-[(R)-1-(3,4-difluorobenzyl)-2-oxo-2-(3-pentyl-3-phenylazetidin-1-yl)ethyl]-3-(1H-imidazol-4-yl)propionamide | US9630949, 53 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H34F2N4O2 |
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| Mol. Mass. | 508.6027 |
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| SMILES | CCCCCC1(CN(C1)C(=O)[C@@H](Cc1ccc(F)c(F)c1)NC(=O)CCc1c[nH]cn1)c1ccccc1 |
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| Structure | 
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