| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 4 [42-168] |
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| Ligand | BDBM50178188 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | BRD4 AlphaLisa Binding Assay |
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| IC50 | 2172±n/a nM |
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| Citation |  Romero, FA; Magnuson, SR; Pastor, R; Tsui, VH; Murray, J; Crawford, T; Burdick, DJ; Albrecht, BK; Cote, A; Taylor, AM; Nasveschuck, CG; LeBlanc, Y; Hewitt, MC; Lai, KW; Chen, K Therapeutic compounds and uses thereof US Patent US10206931 Publication Date 2/19/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 4 [42-168] |
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| Name: | Bromodomain-containing protein 4 [42-168] |
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| Synonyms: | BRD4 | BRD4 BD1 (aa 42-168) | BRD4_HUMAN | Bromodomain-containing protein 4 Bromo Domain 1 | HUNK1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 15054.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O60885[42-168] |
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| Residue: | 127 |
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| Sequence: | STNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKII
KTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI
NELPTEE
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| BDBM50178188 |
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| n/a |
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| Name | BDBM50178188 |
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| Synonyms: | CHEMBL3813731 | US10206931, Example 114 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16N2O3 |
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| Mol. Mass. | 284.3098 |
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| SMILES | C[C@@H]1CC(=O)Nc2ccc(OCc3cccnc3)cc2O1 |r| |
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| Structure | 
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