| Reaction Details |
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 | Report a problem with these data |
| Target | Fascin |
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| Ligand | BDBM350102 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Chemical Library Screens and Analysis |
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| IC50 | 652±n/a nM |
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| Citation |  Huang, X; Shue, CY Methods for inhibiting fascin US Patent US10208043 Publication Date 2/19/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Fascin |
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| Name: | Fascin |
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| Synonyms: | 55 kDa actin-bundling protein | FAN1 | FSCN1 | FSCN1_HUMAN | HSN | SNL | Singed-like protein | p55 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 54533.89 |
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| Organism: | Homo sapiens (human) |
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| Description: | n/a |
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| Residue: | 493 |
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| Sequence: | MTANGTAEAVQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAV
CLRSHLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDGRWSLQSEAHRRYFGGTEDRLS
CFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLA
FQDQRYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTL
KAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDR
DTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKN
GQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEFND
GAYNIKDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKVGGRYLKGDHAGVLKA
SAETVDPASLWEY
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| BDBM350102 |
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| n/a |
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| Name | BDBM350102 |
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| Synonyms: | 2-chloro-N-(6- chlorobenzo[d]thiazol-2- yl)-5- nitrobenzenesulfonamide | US10208043, # 3 | US10941146, # 3 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H7Cl2N3O4S2 |
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| Mol. Mass. | 404.248 |
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| SMILES | [O-][N+](=O)c1ccc(Cl)c(c1)S(=O)(=O)Nc1nc2ccc(Cl)cc2s1 |
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| Structure | 
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