| Reaction Details |
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 | Report a problem with these data |
| Target | Fascin |
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| Ligand | BDBM350104 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Chemical Library Screens and Analysis |
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| IC50 | 500±n/a nM |
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| Citation |  Huang, X; Shue, CY Methods for inhibiting fascin US Patent US10208043 Publication Date 2/19/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Fascin |
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| Name: | Fascin |
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| Synonyms: | 55 kDa actin-bundling protein | FAN1 | FSCN1 | FSCN1_HUMAN | HSN | SNL | Singed-like protein | p55 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 54533.89 |
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| Organism: | Homo sapiens (human) |
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| Description: | n/a |
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| Residue: | 493 |
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| Sequence: | MTANGTAEAVQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAV
CLRSHLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDGRWSLQSEAHRRYFGGTEDRLS
CFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLA
FQDQRYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTL
KAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDR
DTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKN
GQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEFND
GAYNIKDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKVGGRYLKGDHAGVLKA
SAETVDPASLWEY
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| BDBM350104 |
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| n/a |
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| Name | BDBM350104 |
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| Synonyms: | N-methyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amine | US10208043, # 5 | US10941146, # 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N3S |
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| Mol. Mass. | 268.357 |
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| SMILES | CNC1=NC(c2ccccc2)=[N](S1)c1ccccc1 |c:11,t:2| |
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| Structure | 
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