Reaction Details |
| Report a problem with these data |
Target | Free fatty acid receptor 4 |
---|
Ligand | BDBM382126 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | BRET assay |
---|
EC50 | 2750±n/a nM |
---|
Citation | Kumar, S; Sharma, R; Deore, VB; Yewalkar, NN Substituted phenyl alkanoic acid compounds as GPR120 agonists and uses thereof US Patent US10273230 Publication Date 4/30/2019 |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Free fatty acid receptor 4 |
---|
Name: | Free fatty acid receptor 4 |
Synonyms: | FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4 |
Type: | PROTEIN |
Mol. Mass.: | 42256.91 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1508994 |
Residue: | 377 |
Sequence: | MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC
ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL
SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV
PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDA
RAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITI
LLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGA
ILTDTSVKRNDLSIISG
|
|
|
BDBM382126 |
---|
n/a |
---|
Name | BDBM382126 |
Synonyms: | 4-(4-((4'-(1-cyanocyclopropyl)-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methoxy)phenyl) butanoic Acid | US10273230, Compound of Example 1 |
Type | Small organic molecule |
Emp. Form. | C27H29NO3 |
Mol. Mass. | 415.5241 |
SMILES | OC(=O)CCCc1ccc(OCC2=C(CCCC2)c2ccc(cc2)C2(CC2)C#N)cc1 |t:12| |
Structure |
|