| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM387080 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Assay |
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| Ki | >1000±n/a nM |
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| Citation |  Ding, Z; Lai, G; Chen, S; Yan, X Hydrazine compound as blood coagulation factor Xa inhibitor US Patent US9938272 Publication Date 4/10/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM387080 |
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| n/a |
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| Name | BDBM387080 |
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| Synonyms: | 4-(4-(1-(3-Aminobenzo[d]isoxazol-5-yl)-7-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)piperidin-1-yl)morpholin-3-one | US9938272, Example 26 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24F3N7O4 |
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| Mol. Mass. | 519.4764 |
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| SMILES | Nc1noc2ccc(cc12)-n1nc(c2CCN(C3CCN(CC3)N3CCOCC3=O)C(=O)c12)C(F)(F)F |
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| Structure | 
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