| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM42421 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1) |
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| IC50 | 18920±n/a nM |
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| Citation |  PubChem, PC Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1) PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM42421 |
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| n/a |
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| Name | BDBM42421 |
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| Synonyms: | 2-[[[2-(4-chlorophenyl)-5-methyl-3-pyrazolyl]amino]methylidene]propanedioic acid diethyl ester | 2-[[[2-(4-chlorophenyl)-5-methyl-pyrazol-3-yl]amino]methylene]malonic acid diethyl ester | MLS000541363 | SMR000126221 | cid_3849628 | diethyl 2-({[1-(4-chlorophenyl)-3-methyl-1H-pyrazol-5-yl]amino}methylene)malonate | diethyl 2-[[[2-(4-chlorophenyl)-5-methyl-pyrazol-3-yl]amino]methylidene]propanedioate | diethyl 2-[[[2-(4-chlorophenyl)-5-methylpyrazol-3-yl]amino]methylidene]propanedioate |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20ClN3O4 |
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| Mol. Mass. | 377.822 |
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| SMILES | CCOC(=O)C(C=Nc1cc(C)nn1-c1ccc(Cl)cc1)C(=O)OCC |w:7.7| |
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| Structure | 
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