BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSignal transducer and activator of transcription 3 [702-738,740-752]
LigandBDBM43547
Substrate/Competitorn/a
Meas. Tech.Dose response cell-based assay to measure STAT3 activation
IC50 5095±n/a nM
Citation PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Signal transducer and activator of transcription 3 [702-738,740-752]
Name:Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:APRF | STAT3 | STAT3_HUMAN
Type:Enzyme Catalytic Domain
Mol. Mass.:5263.93
Organism:Homo sapiens (Human)
Description:gi_13272532
Residue:50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM43547
n/a
NameBDBM43547
Synonyms:(3-Cyano-2-methyl-indol-1-yl)-acetic acid | 2-(3-cyano-2-methyl-1-indolyl)acetic acid | 2-(3-cyano-2-methyl-indol-1-yl)acetic acid | 2-(3-cyano-2-methyl-indol-1-yl)ethanoic acid | 2-(3-cyano-2-methylindol-1-yl)acetic acid | MLS000075634 | SMR000013849 | cid_653215
TypeSmall organic molecule
Emp. Form.C12H10N2O2
Mol. Mass.214.22
SMILESCc1c(C#N)c2ccccc2n1CC(O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: