| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 1-alpha/beta |
|---|
| Ligand | BDBM43634 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response counterscreen assay for STAT3 activators: cell-based high throughput assay to measure STAT1 activation |
|---|
| EC50 | >55700±n/a nM |
|---|
| Citation |  PubChem, PC Dose response counterscreen assay for STAT3 activators: cell-based high throughput assay to measure STAT1 activation PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Signal transducer and activator of transcription 1-alpha/beta |
|---|
| Name: | Signal transducer and activator of transcription 1-alpha/beta |
|---|
| Synonyms: | STAT1 | STAT1_HUMAN | Signal transducer and activator of transcription 1-alpha/beta | Transcription Factor STAT1 | Transcription factor ISGF-3 components p91/p84 | signal transducer and activator of transcription 1 isoform alpha |
|---|
| Type: | Cytosolic Transcription Factor |
|---|
| Mol. Mass.: | 87327.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Stat1 was expressed in sf9 cells from a baculovirus encoding the recombinant proteins. Stat1 dimer binds to DNA. |
|---|
| Residue: | 750 |
|---|
| Sequence: | MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDL
LSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQ
RFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKTLQNR
EHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLNVTELTQNALINDELVEWK
RRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQV
LWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKV
KVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGTRTN
EGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAE
PRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGLIPWT
RFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFL
LRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIP
ENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEVHPSRLQTT
DNLLPMSPEEFDEVSRIVGSVEFDSMMNTV
|
|
|
|---|
| BDBM43634 |
|---|
| n/a |
|---|
| Name | BDBM43634 |
|---|
| Synonyms: | 2-methyl-N-[4-[(o-anisoylamino)carbamoyl]phenyl]propionamide | MLS000672334 | N-(4-{[2-(2-methoxybenzoyl)hydrazino]carbonyl}phenyl)-2-methylpropanamide | N-[4-[[(2-methoxybenzoyl)amino]carbamoyl]phenyl]-2-methylpropanamide | N-[4-[[(2-methoxyphenyl)carbonylamino]carbamoyl]phenyl]-2-methyl-propanamide | N-[4-[[[(2-methoxyphenyl)-oxomethyl]hydrazo]-oxomethyl]phenyl]-2-methylpropanamide | SMR000295764 | cid_1242183 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H21N3O4 |
|---|
| Mol. Mass. | 355.3877 |
|---|
| SMILES | COc1ccccc1C(=O)NNC(=O)c1ccc(NC(=O)C(C)C)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
