| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor coactivator 3 |
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| Ligand | BDBM42925 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) |
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| EC50 | >79370±n/a nM |
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| Citation |  PubChem, PC Dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Nuclear receptor coactivator 3 |
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| Name: | Nuclear receptor coactivator 3 |
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| Synonyms: | AIB1 | BHLHE42 | NCOA3 | NCOA3_HUMAN | RAC3 | TRAM1 | nuclear receptor coactivator 3 isoform a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 155305.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y6Q9 |
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| Residue: | 1424 |
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| Sequence: | MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDID
NFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQA
LDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGE
DLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRC
IQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR
HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA
DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNI
MISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST
LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKE
SSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVS
SSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN
VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQE
KDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK
SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS
SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPT
LPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQV
SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE
LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMN
QMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTA
GGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ
QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQ
PDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQ
FAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC
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| BDBM42925 |
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| n/a |
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| Name | BDBM42925 |
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| Synonyms: | (2E)-2-(3-methyl-1H-benzimidazol-2-ylidene)-4-(2-naphthalenyloxy)-3-oxobutanenitrile | (2E)-2-(3-methyl-1H-benzimidazol-2-ylidene)-4-naphthalen-2-yloxy-3-oxidanylidene-butanenitrile | (2E)-2-(3-methyl-1H-benzimidazol-2-ylidene)-4-naphthalen-2-yloxy-3-oxobutanenitrile | (2E)-3-keto-2-(3-methyl-1H-benzimidazol-2-ylidene)-4-(2-naphthoxy)butyronitrile | MLS000055275 | SMR000061763 | cid_5742548 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H17N3O2 |
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| Mol. Mass. | 355.3893 |
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| SMILES | Cn1c(nc2ccccc12)C(C#N)C(=O)COc1ccc2ccccc2c1 |
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| Structure | 
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