Reaction Details |
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Target | Signal transducer and activator of transcription 3 [702-738,740-752] |
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Ligand | BDBM46337 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response cell-based assay to measure STAT3 inhibition |
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IC50 | 5020±n/a nM |
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Citation | PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Signal transducer and activator of transcription 3 [702-738,740-752] |
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Name: | Signal transducer and activator of transcription 3 [702-738,740-752] |
Synonyms: | APRF | STAT3 | STAT3_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 5263.93 |
Organism: | Homo sapiens (Human) |
Description: | gi_13272532 |
Residue: | 50 |
Sequence: | AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
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BDBM46337 |
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n/a |
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Name | BDBM46337 |
Synonyms: | 1-[5-(4-Chloro-benzylsulfanyl)-[1,3,4]oxadiazol-2-ylmethyl]-1H-benzoimidazole | 2-(1-benzimidazolylmethyl)-5-[(4-chlorophenyl)methylthio]-1,3,4-oxadiazole | 2-(benzimidazol-1-ylmethyl)-5-[(4-chlorobenzyl)thio]-1,3,4-oxadiazole | 2-(benzimidazol-1-ylmethyl)-5-[(4-chlorophenyl)methylsulfanyl]-1,3,4-oxadiazole | MLS000030897 | SMR000001594 | cid_646906 |
Type | Small organic molecule |
Emp. Form. | C17H13ClN4OS |
Mol. Mass. | 356.829 |
SMILES | Clc1ccc(CSc2nnc(Cn3cnc4ccccc34)o2)cc1 |
Structure |
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