Reaction Details |
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Target | Signal transducer and activator of transcription 3 [702-738,740-752] |
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Ligand | BDBM46396 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response cell-based assay to measure STAT3 inhibition |
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IC50 | 3700±n/a nM |
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Citation | PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Signal transducer and activator of transcription 3 [702-738,740-752] |
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Name: | Signal transducer and activator of transcription 3 [702-738,740-752] |
Synonyms: | APRF | STAT3 | STAT3_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 5263.93 |
Organism: | Homo sapiens (Human) |
Description: | gi_13272532 |
Residue: | 50 |
Sequence: | AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
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BDBM46396 |
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n/a |
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Name | BDBM46396 |
Synonyms: | MLS000589892 | N-(3-Hydroxy-phenyl)-N'-pyridin-2-yl-oxalamide | N-(3-hydroxyphenyl)-N'-(2-pyridinyl)oxamide | N-(3-hydroxyphenyl)-N'-(2-pyridyl)oxamide | N-(3-hydroxyphenyl)-N'-pyridin-2-yl-ethanediamide | N-(3-hydroxyphenyl)-N'-pyridin-2-yloxamide | SMR000217071 | cid_1898255 |
Type | Small organic molecule |
Emp. Form. | C13H11N3O3 |
Mol. Mass. | 257.2447 |
SMILES | Oc1cccc(NC(=O)C(=O)Nc2ccccn2)c1 |
Structure |
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