| Reaction Details |
|---|
 | Report a problem with these data |
| Target | E3 ubiquitin-protein ligase Mdm2 |
|---|
| Ligand | BDBM43457 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | E3 Ligase_Mutant_Dose Response |
|---|
| EC50 | 1720±n/a nM |
|---|
| Citation |  PubChem, PC E3 Ligase_Mutant_Dose Response PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| E3 ubiquitin-protein ligase Mdm2 |
|---|
| Name: | E3 ubiquitin-protein ligase Mdm2 |
|---|
| Synonyms: | Double minute 2 protein | Double minute 2 protein (HDM2) | E3 ubiquitin-protein ligase Mdm2 (p53-binding protein Mdm2) | Hdm2 | Human Double Minute 2 (HDM2) | MDM2 | MDM2-MDMX | MDM2_HUMAN | p53-Binding Protein MDM2 | p53-binding protein |
|---|
| Type: | Oncoprotein |
|---|
| Mol. Mass.: | 55196.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q00987 |
|---|
| Residue: | 491 |
|---|
| Sequence: | MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY
IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT
SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ
RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDS
VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLA
DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP
DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ
DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ
PIQMIVLTYFP
|
|
|
|---|
| BDBM43457 |
|---|
| n/a |
|---|
| Name | BDBM43457 |
|---|
| Synonyms: | (E)-1-(1-benzimidazolyl)-3-(3-nitrophenyl)-2-propen-1-one | (E)-1-(benzimidazol-1-yl)-3-(3-nitrophenyl)prop-2-en-1-one | MLS000688769 | SMR000285852 | cid_5757382 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H11N3O3 |
|---|
| Mol. Mass. | 293.2768 |
|---|
| SMILES | [O-][N+](=O)c1cccc(\C=C\C(=O)n2cnc3ccccc23)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
