| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mucolipin-3 |
|---|
| Ligand | BDBM46749 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence counterscreen assay for TRPN1 agonists: dose response cell-based high-throughput screening assay to identify agonists of the transient receptor potential channel ML3 (TRPML3) |
|---|
| EC50 | 29900±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescence counterscreen assay for TRPN1 agonists: dose response cell-based high-throughput screening assay to identify agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mucolipin-3 |
|---|
| Name: | Mucolipin-3 |
|---|
| Synonyms: | MCLN3_HUMAN | MCOLN3 | MCOLN3 protein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 64244.09 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8TDD5 |
|---|
| Residue: | 553 |
|---|
| Sequence: | MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA
MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI
YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE
DDPPVSLFCCCKK
|
|
|
|---|
| BDBM46749 |
|---|
| n/a |
|---|
| Name | BDBM46749 |
|---|
| Synonyms: | 1-acetyl-3-(2,6-dimethyl-4-pyranylidene)-2-indolone | 1-acetyl-3-(2,6-dimethyl-4H-pyran-4-ylidene)-1,3-dihydro-2H-indol-2-one | 1-acetyl-3-(2,6-dimethylpyran-4-ylidene)indol-2-one | 1-acetyl-3-(2,6-dimethylpyran-4-ylidene)oxindole | 3-(2,6-dimethylpyran-4-ylidene)-1-ethanoyl-indol-2-one | MLS000043288 | SMR000019908 | cid_697318 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H15NO3 |
|---|
| Mol. Mass. | 281.3059 |
|---|
| SMILES | [#6]-[#6](=O)-[#7]-1-[#6](=O)\[#6](-c2ccccc-12)=[#6]-1\[#6]=[#6](-[#6])-[#8]-[#6](-[#6])=[#6]-1 |c:21,t:16| |
|---|
| Structure | 
|
|---|
Search and Browse
