Ki Summary

Reaction Details

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Target

Zinc finger protein mex-5

Ligand

BDBM44480

Substrate/Competitor

n/a

Meas. Tech.

Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2

EC50

300000±n/a nM

Citation

PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Zinc finger protein mex-5

Name:

Zinc finger protein mex-5

Synonyms:

MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5

Type:

Enzyme Catalytic Domain

Mol. Mass.:

52832.78

Organism:

Caenorhabditis elegans

Description:

gi_55976631

Residue:

468

Sequence:

MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNG
SSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQP
QLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTA
PLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAE
KENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKE
LRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDD
QDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGD
YNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY

BDBM44480

n/a

Name

BDBM44480

Synonyms:

1-(3-Amino-6-thiophen-2-yl-4-trifluoromethyl-thieno[2,3-b]pyridin-2-yl)-2,2-dimethyl-propan-1-one | 1-[3-amino-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-2,2-dimethyl-propan-1-one | 1-[3-amino-6-thiophen-2-yl-4-(trifluoromethyl)-2-thieno[2,3-b]pyridinyl]-2,2-dimethyl-1-propanone | 1-[3-amino-6-thiophen-2-yl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one | 1-[3-azanyl-6-thiophen-2-yl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-2,2-dimethyl-propan-1-one | MLS000558164 | SMR000148880 | cid_1272770

Type

Small organic molecule

Emp. Form.

C17H15F3N2OS2

Mol. Mass.

384.439

SMILES

CC(C)(C)C(=O)c1sc2nc(cc(c2c1N)C(F)(F)F)-c1cccs1

Structure