| Reaction Details |
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 | Report a problem with these data |
| Target | Nucleotide-binding oligomerization domain-containing protein 2 |
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| Ligand | BDBM30719 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS luminescence assay for the identification of compounds that inhibit NOD2 in MDP treated cells |
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| IC50 | 4356±n/a nM |
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| Citation |  PubChem, PC uHTS luminescence assay for the identification of compounds that inhibit NOD2 in MDP treated cells PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Nucleotide-binding oligomerization domain-containing protein 2 |
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| Name: | Nucleotide-binding oligomerization domain-containing protein 2 |
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| Synonyms: | CARD15 | Caspase recruitment domain-containing protein 15 | IBD1 | Inflammatory bowel disease protein 1 | NOD2 | NOD2_HUMAN | Nucleotide-binding oligomerization domain-containing protein 2 | nucleotide-binding oligomerization domain containing 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 115287.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1454053 |
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| Residue: | 1040 |
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| Sequence: | MGEEGGSASHDEEERASVLLGHSPGCEMCSQEAFQAQRSQLVELLVSGSLEGFESVLDWL
LSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLH
GCWDPHSLHPARDLQSHRPAIVRRLHSHVENMLDLAWERGFVSQYECDEIRLPIFTPSQR
ARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCKKYMAKLRTTVSAQSRFLSTY
DGAETLCLEDIYTENVLEVWADVGMAGPPQKSPATLGLEELFSTPGHLNDDADTVLVVGE
AGSGKSTLLQRLHLLWAAGQDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQ
EDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNAR
KVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPGVADRLIRLLQETSALH
GLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHATPPDSASQGLGPSLL
RGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLE
FLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPMARLLPTMCIQASEGKDSSVA
ALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFH
SIPPAAPGEAKSVHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPTECA
ALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECAL
HCEQLQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTS
LQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEEL
CLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVWLRG
NTFSLEEVDKLGCRDTRLLL
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| BDBM30719 |
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| n/a |
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| Name | BDBM30719 |
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| Synonyms: | (3E)-6-hexyl-3-[(5E)-5-(6-ketocyclohexa-2,4-dien-1-ylidene)-1,3,4-oxadiazolidin-2-ylidene]chromene-2,7-quinone | (3E)-6-hexyl-3-[(5E)-5-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)-1,3,4-oxadiazolidin-2-ylidene]chromene-2,7-dione | (3E)-6-hexyl-3-[(5E)-5-(6-oxo-1-cyclohexa-2,4-dienylidene)-1,3,4-oxadiazolidin-2-ylidene]-1-benzopyran-2,7-dione | (3E)-6-hexyl-3-[(5E)-5-(6-oxocyclohexa-2,4-dien-1-ylidene)-1,3,4-oxadiazolidin-2-ylidene]chromene-2,7-dione | MLS000079474 | SMR000036273 | cid_5389090 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N2O5 |
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| Mol. Mass. | 406.4312 |
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| SMILES | CCCCCCC1=Cc2c\c(=C3\NN\C(O3)=C3\C=CC=CC3=O)c(=O)oc2=CC1=O |c:18,20,29,t:6| |
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| Structure | 
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