Reaction Details |
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Target | 2'-phosphotransferase |
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Ligand | BDBM46749 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). |
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IC50 | >2063±n/a nM |
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Citation | PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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2'-phosphotransferase |
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Name: | 2'-phosphotransferase |
Synonyms: | likely tRNA 2'-phosphotransferase |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 23631.37 |
Organism: | Candida albicans SC5314 |
Description: | gi_68476498 |
Residue: | 207 |
Sequence: | MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDIN
RIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIK
SSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSG
DKDGKLSWEFIDRIVGLDGNEINKEQV
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BDBM46749 |
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n/a |
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Name | BDBM46749 |
Synonyms: | 1-acetyl-3-(2,6-dimethyl-4-pyranylidene)-2-indolone | 1-acetyl-3-(2,6-dimethyl-4H-pyran-4-ylidene)-1,3-dihydro-2H-indol-2-one | 1-acetyl-3-(2,6-dimethylpyran-4-ylidene)indol-2-one | 1-acetyl-3-(2,6-dimethylpyran-4-ylidene)oxindole | 3-(2,6-dimethylpyran-4-ylidene)-1-ethanoyl-indol-2-one | MLS000043288 | SMR000019908 | cid_697318 |
Type | Small organic molecule |
Emp. Form. | C17H15NO3 |
Mol. Mass. | 281.3059 |
SMILES | [#6]-[#6](=O)-[#7]-1-[#6](=O)\[#6](-c2ccccc-12)=[#6]-1\[#6]=[#6](-[#6])-[#8]-[#6](-[#6])=[#6]-1 |c:21,t:16| |
Structure |
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