| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Genome polyprotein |
|---|
| Ligand | BDBM29685 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3). |
|---|
| IC50 | 12591±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3). PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Genome polyprotein |
|---|
| Name: | Genome polyprotein |
|---|
| Synonyms: | NS3 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 67067.41 |
|---|
| Organism: | Hepatitis C virus |
|---|
| Description: | gi_125541954 |
|---|
| Residue: | 631 |
|---|
| Sequence: | APITAYAQQTRGLLGCIITGLTGRDKNQVEGEVQIVSTAAQTFLATCINGVCWTVYHGAG
TRTIASSKGPVIQMYTNVDQDLVGWPAPQGARSLTPCTCGSSDLYLVTRHADVIPVRRRG
DGRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVCTRGVAKAVDFIPVEGLETTMR
SPVFSDNSSPPAVPQSYQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGA
YMSKAHGIDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGSAYDIIICDECHSTDATSI
LGIGTVLDQAETAGARLTVLATATPPGSVTVPHPNIEEVALSTTGEIPFYGKAIPLEAIK
GGRHLIFCHSKKKCDELAAKLVALGVNAVAYYRGLDVSVIPASGDVVVVATDALMTGFTG
DFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVTPGE
RPSGMFDSSVLCECYDAGCAWYELTPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLT
HIDAHFLSQTKQSGENLPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLY
RLGAVQNEITLTHPITKYIMTCMSADLEVVT
|
|
|
|---|
| BDBM29685 |
|---|
| n/a |
|---|
| Name | BDBM29685 |
|---|
| Synonyms: | (3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopenta[b]quinoline-9-carboxylic acid [2-(cyclopentylamino)-2-oxoethyl] ester | (3E)-3-(2-furfurylidene)-1,2-dihydrocyclopenta[b]quinoline-9-carboxylic acid [2-(cyclopentylamino)-2-keto-ethyl] ester | MLS000333913 | SMR000248671 | [2-(cyclopentylamino)-2-oxidanylidene-ethyl] (3E)-3-(furan-2-ylmethylidene)-1,2-dihydrocyclopenta[b]quinoline-9-carboxylate | [2-(cyclopentylamino)-2-oxoethyl] (3E)-3-(furan-2-ylmethylidene)-1,2-dihydrocyclopenta[b]quinoline-9-carboxylate | cid_6092126 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H24N2O4 |
|---|
| Mol. Mass. | 416.4691 |
|---|
| SMILES | O=C(COC(=O)c1c2CC\C(=C/c3ccco3)c2nc2ccccc12)NC1CCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
