Ki Summary

Reaction Details

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Target

Streptokinase A

Ligand

BDBM34736

Substrate/Competitor

n/a

Meas. Tech.

Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression

EC50

150000±n/a nM

Citation

PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Streptokinase A

Name:

Streptokinase A

Synonyms:

STRP_STRP1 | ska | streptokinase A precursor

Type:

Enzyme Catalytic Domain

Mol. Mass.:

49924.80

Organism:

Streptococcus pyogenes M1 GAS

Description:

gi_15675770

Residue:

440

Sequence:

MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVF
INFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSN
DGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQ
AKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGY
TIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKY
YVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAK
LLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEER
KAYSYLRDTGTPIPDNPKDK

BDBM34736

n/a

Name

BDBM34736

Synonyms:

1,4-diketo-3-(4-methoxyphenyl)naphthalene-2-carboxylic acid ethyl ester | 3-(4-methoxyphenyl)-1,4-dioxo-2-naphthalenecarboxylic acid ethyl ester | MLS000573105 | SMR000185036 | cid_790561 | ethyl 3-(4-methoxyphenyl)-1,4-bis(oxidanylidene)naphthalene-2-carboxylate | ethyl 3-(4-methoxyphenyl)-1,4-dioxo-1,4-dihydro-2-naphthalenecarboxylate | ethyl 3-(4-methoxyphenyl)-1,4-dioxonaphthalene-2-carboxylate

Type

Small organic molecule

Emp. Form.

C20H16O5

Mol. Mass.

336.338

SMILES

CCOC(=O)C1=C(C(=O)c2ccccc2C1=O)c1ccc(OC)cc1 |t:5|

Structure