BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetE3 ubiquitin-protein ligase XIAP
LigandBDBM59366
Substrate/Competitorn/a
Meas. Tech.Chemical Antagonists IAP-family anti-apoptotic proteins
IC50 100000±n/a nM
Citation PubChem, PC Chemical Antagonists IAP-family anti-apoptotic proteins PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
E3 ubiquitin-protein ligase XIAP
Name:E3 ubiquitin-protein ligase XIAP
Synonyms:API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN
Type:Protein
Mol. Mass.:56685.27
Organism:Homo sapiens (Human)
Description:P98170
Residue:497
Sequence:
MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT
VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY
LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT
PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE
SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC
FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP
SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD
SMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK
CPMCYTVITFKQKIFMS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM59366
n/a
NameBDBM59366
Synonyms:1-(4-methoxy-2,3-dimethyl-phenyl)sulfonylpyrrolidine | 1-(4-methoxy-2,3-dimethylphenyl)sulfonylpyrrolidine | 1-[(4-methoxy-2,3-dimethylphenyl)sulfonyl]pyrrolidine | MLS000063948 | SMR000076860 | cid_970938
TypeSmall organic molecule
Emp. Form.C13H19NO3S
Mol. Mass.269.36
SMILESCOc1ccc(c(C)c1C)S(=O)(=O)N1CCCC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: