Reaction Details |
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Target | E3 ubiquitin-protein ligase XIAP |
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Ligand | BDBM59366 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Chemical Antagonists IAP-family anti-apoptotic proteins |
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IC50 | 100000±n/a nM |
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Citation | PubChem, PC Chemical Antagonists IAP-family anti-apoptotic proteins PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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E3 ubiquitin-protein ligase XIAP |
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Name: | E3 ubiquitin-protein ligase XIAP |
Synonyms: | API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN |
Type: | Protein |
Mol. Mass.: | 56685.27 |
Organism: | Homo sapiens (Human) |
Description: | P98170 |
Residue: | 497 |
Sequence: | MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT
VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY
LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT
PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE
SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC
FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP
SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD
SMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK
CPMCYTVITFKQKIFMS
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BDBM59366 |
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n/a |
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Name | BDBM59366 |
Synonyms: | 1-(4-methoxy-2,3-dimethyl-phenyl)sulfonylpyrrolidine | 1-(4-methoxy-2,3-dimethylphenyl)sulfonylpyrrolidine | 1-[(4-methoxy-2,3-dimethylphenyl)sulfonyl]pyrrolidine | MLS000063948 | SMR000076860 | cid_970938 |
Type | Small organic molecule |
Emp. Form. | C13H19NO3S |
Mol. Mass. | 269.36 |
SMILES | COc1ccc(c(C)c1C)S(=O)(=O)N1CCCC1 |
Structure |
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