| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM54803 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay |
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| IC50 | 1880±n/a nM |
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| Citation |  PubChem, PC uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM54803 |
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| n/a |
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| Name | BDBM54803 |
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| Synonyms: | (phenylmethyl) N-[2,2,2-tris(chloranyl)-1-[[2,4,6-tris(chloranyl)phenyl]carbamothioylamino]ethyl]carbamate | MLS000562423 | N-[2,2,2-trichloro-1-[(2,4,6-trichlorophenyl)thiocarbamoylamino]ethyl]carbamic acid benzyl ester | N-[2,2,2-trichloro-1-[[sulfanylidene-(2,4,6-trichloroanilino)methyl]amino]ethyl]carbamic acid (phenylmethyl) ester | SMR000173876 | benzyl N-[2,2,2-trichloro-1-[(2,4,6-trichlorophenyl)carbamothioylamino]ethyl]carbamate | cid_3091267 | {2,2,2-Trichloro-1-[3-(2,4,6-trichloro-phenyl)-thioureido]-ethyl}-carbamic acid benzyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13Cl6N3O2S |
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| Mol. Mass. | 536.087 |
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| SMILES | Clc1cc(Cl)c(NC(=S)NC(NC(=O)OCc2ccccc2)C(Cl)(Cl)Cl)c(Cl)c1 |
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| Structure | 
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