| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Polyadenylate-binding protein 1 |
|---|
| Ligand | BDBM51503 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) |
|---|
| IC50 | 100000±n/a nM |
|---|
| Citation |  PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Polyadenylate-binding protein 1 |
|---|
| Name: | Polyadenylate-binding protein 1 |
|---|
| Synonyms: | PAB1 | PABP | PABP1 | PABP1_HUMAN | PABPC1 | PABPC2 | poly(A) binding protein, cytoplasmic 1 | polyadenylate-binding protein 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 70694.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_46367787 |
|---|
| Residue: | 636 |
|---|
| Sequence: | MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
|
|
|
|---|
| BDBM51503 |
|---|
| n/a |
|---|
| Name | BDBM51503 |
|---|
| Synonyms: | 2-[8-(diethylaminomethyl)-7-hydroxy-2-keto-4-methyl-chromen-3-yl]acetic acid methyl ester;hydrochloride | 2-[8-(diethylaminomethyl)-7-hydroxy-4-methyl-2-oxo-1-benzopyran-3-yl]acetic acid methyl ester;hydrochloride | MLS000081528 | SMR000043423 | cid_6603244 | methyl 2-[8-(diethylaminomethyl)-4-methyl-7-oxidanyl-2-oxidanylidene-chromen-3-yl]ethanoate;hydrochloride | methyl 2-[8-(diethylaminomethyl)-7-hydroxy-4-methyl-2-oxochromen-3-yl]acetate;hydrochloride |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H23NO5 |
|---|
| Mol. Mass. | 333.3789 |
|---|
| SMILES | CCN(CC)Cc1c(O)ccc2c(C)c(CC(=O)OC)c(=O)oc12 |
|---|
| Structure | 
|
|---|
Search and Browse
